1.0 mg/mL in acetonitrile: water (1:1), ampule of 1 mL, certified reference material
Synonym: 3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl
phosphate solution
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Empirical Formula
(Hill Notation) C12H17N2O4P
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Molecular
Weight 284.25
Properties
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Related Categories
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grade
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certified reference material
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feature
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(Snap-N-Spike®)
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packaging
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ampule of 1 mL
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drug control
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Narcotic Licence Schedule D (Switzerland);
psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)
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concentration
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1.0 mg/mL in acetonitrile: water (1:1)
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storage temp.
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−70°C
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Psilocybin is a naturally occurring psychedelic compound produced by more than 200
species of mushrooms, collectively known as psilocybin
mushrooms.
Detailed description
The most potent are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera. As a prodrug, psilocybin is quickly converted by the body
to psilocin, which has
mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT. In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and spiritual
experiences, and can include possible adverse reactions such as nausea and panic attacks.
Imagery found on prehistoric murals and rock paintings of modern-day Spain
and Algeria suggests that human usage of psilocybin mushrooms dates back thousands
of years. In Mesoamerica, the mushrooms had
long been consumed in spiritual and divinatory ceremonies before
Spanish chroniclers first documented their use in the 16th century. In a 1957 Life magazine article,
American banker and ethnomycologist R. Gordon Wasson described his
experiences ingesting psilocybin-containing mushrooms during a traditional
ceremony in Mexico, introducing the substance to popular culture. In 1959, the
Swiss chemist Albert Hofmann isolated the active
principle psilocybin from the mushroom Psilocybe mexicana.
Hofmann's employer Sandoz marketed and sold
pure psilocybin to physicians and clinicians worldwide for use in psychedelic psychotherapy. Although the increasingly restrictive drug laws of the late
1960s curbed scientific research into the effects of psilocybin and other
hallucinogens, its popularity as an entheogen (spirituality-enhancing
agent) grew in the next decade, owing largely to the increased availability of
information on how to cultivate psilocybin mushrooms.
Some users of the drug consider it an entheogen and
a tool to supplement practices for transcendence, including meditation and psychonautics. The intensity and duration of the
effects of psilocybin are variable, depending on species or cultivar of mushrooms,
dosage, individual physiology, and set and setting, as was shown in
experiments led by Timothy Leary at Harvard University in the early 1960s.
Once ingested, psilocybin is rapidly metabolized to psilocin, which then acts
on serotonin receptors in the brain. The
mind-altering effects of psilocybin typically last from two to six hours,
although to individuals under the influence of psilocybin, the effects may seem
to last much longer, since the drug can distort the perception of time.
Psilocybin has a low toxicity and a relatively low
harm potential, and reports of lethal doses of the drug are rare. Several
modern bioanalytical methods
have been adapted to rapidly and accurately screen the levels of psilocybin in
mushroom samples and body fluids. Since the 1990s, there has been a renewal of
scientific research into the potential medical and psychological therapeutic
benefits of psilocybin for treating conditions including obsessive-compulsive
disorder (OCD), post-traumatic
stress disorder, social anxiety, cluster headaches, and anxiety
related to terminal cancer.[4] Possession of
psilocybin-containing mushrooms has been outlawed in most countries, and it has
been classified as a scheduled drug by many national drug laws.
PRICE
$265455.22/KG OR $120661.46/IB
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