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CAS Number 7758-19-2
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Linear Formula NaClO2
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Molecular Weight 90.44
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EC Number 231-836-6
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MDL number MFCD00003478
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PubChem Substance ID 329763228
Sodium Chlorite (NaClO2)
is a chemical compound used in the manufacturing of paper and as a disinfectant.
Detailed description
Use
The main application of Sodium chlorite is the
generation of Chlorine
dioxide for bleaching and stripping of textiles, pulp, and paper. It is
also used for disinfection of municipal water treatment plants after conversion
to chlorine dioxide.[1]:2 An advantage in this
application, as compared to the more commonly used chlorine, is that trihalomethanes (such as chloroform) are not produced from organic contaminants.[1]:25,33 Chlorine
dioxide generated from sodium chlorite is approved by FDA under some
conditions for disinfecting water used to wash fruits, vegetables, and poultry.[2]
Sodium chlorite, NaClO2, sometimes in
combination with zinc
chloride, also finds application as a component in
therapeutic rinses, mouthwashes,[3][4] toothpastes and gels, mouth
sprays,[5] as preservative in
eye drops,[6] and in contact lens
cleaning solution under the trade name Purite.
Under the brand name Oxine it is used for sanitizing
air ducts and HVAC/R systems and animal containment areas (walls, floors, and
other surfaces).
Neuraltus Pharmaceuticals is investigating a drug
that they refer to as NP001 for treatment of amyotrophic lateral sclerosis. Some people with ALS have concluded that NP001 is a
formulation of sodium chlorite, and are ordering the chemical and self-dosing
outside of any scientific study. Preliminary results suggest that this sodium chlorite
treatment is less effective than NP001.[7] One seller of “Miracle Mineral Solution” (a mixture of sodium chlorite and citric acid also known as
"MMS").[8]
Chemical reagent
In organic
synthesis, Sodium Chlorite is frequently used as a reagent in
the Pinnick
oxidation for the oxidation of Aldehydes to Carboxylic
acids. The reaction is usually performed in monosodium phosphate buffered solution in
the presence of a chlorine scavenger (usually 2-methyl-2-butene).[9]
Recently, Sodium chlorite has been used as an
oxidizing agent to convert Alkyl furans to the corresponding 4-oxo-2-alkenoic
acids in a simple one pot synthesis.[10]
Acidified sodium chlorite
Mixing sodium chlorite solution with a weak
food-grade acid solution (commonly Citric
acid), both stable, produces short-lived acidified
sodium chlorite (ASC) which has potent decontaminating properties. Upon mixing
the main active ingredient, chlorous
acid is produced in equilibrium with chlorite anion. The proportion
varies with pH, temperature, and other factors, ranging from approximately
5–35% Chlorous
acid with 65–95% Chlorite; more acidic solutions result in a higher proportion of
chlorous acid. Chlorous acid breaks down to chlorine dioxide which in turn
breaks down to chlorite anion and ultimately chloride anion. ASC is used for
sanitation of the hard surfaces which come in contact with food and as a wash
or rinse for a variety of foods including red meat, poultry, seafood, fruits
and vegetables. Because the oxo-chlorine compounds are unstable when properly
prepared, there should be no measurable residue on food if treated
appropriately.[11][12] ASC also is used as
a teat dip for control of mastitis in dairy cattle.
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