United
States Pharmacopeia (USP) Reference Standard
Synonym: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-
benzopyran-4-one
dihydrate, 3,3′,4′,5,7-
Pentahydroxyflavone dihydrate, Quercetin dihydrate
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CAS Number 6151-25-3
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Empirical Formula (Hill Notation) C15H10O7 ·
2H2O
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Molecular Weight 338.27
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Beilstein Registry Number 317313
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Colour Index Number 75670
Properties
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Related Categories
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mp
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>300 °C(lit.)
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Quercetin is a flavonol found in many fruits, vegetables,
leaves, and grains. It can be used as an ingredient in supplements, beverages,
or foods.
Detailed
description
Health effects
While quercetin supplements have been promoted for
prevention and treatment of cancer, "there is no reliable clinical
evidence that quercetin can prevent or treat cancer in humans".[2] Also, there is no
evidence that consuming foods rich in quercetin reduces the risk of cancer or
any other disease.[3]
Quercetin supplements have also been promoted for
the treatment of a wide spectrum of other diseases.[4] However, the European Food Safety
Authority evaluated possible health claims associated with consumption of
quercetin, and found that no cause-and-effect relationship has been established
for any physiological effect in human health or diseases.[5]
Drug interactions
Quercetin is contraindicated with some antibiotics;
it may interact with fluoroquinolones (a class of antibiotics), as quercetin
competitively binds to bacterial DNA gyrase. Whether this inhibits or enhances the
effect of fluoroquinolones is not certain.[6]
As paclitaxel is
metabolized primarily by CYP2C8, its bioavailability may be increased
unpredictably by quercetin, potentially leading to harmful side effects.
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