AJMALICINE,ᵟ-YOHIMBINE OR RAUBASINE ALKALOID

Synonym: δ-Yohimbine, Py-Tetrahydroserpentine, Raubasine

·         CAS Number 483-04-5

·         Empirical Formula (Hill Notation) C₂₁H₂₄N₂O₃

·         Molecular Weight 352.43

·          Beilstein Registry Number 97268

·          EC Number 207-589-5

Properties

Related Categories	Cell Biology, Metabolic Pathways, Metabolomics,Terpenoid Metabolism, Terpenoids More...
assay	≥98.0% (HPLC)
optical activity	[α]/D -65±3°, c = 1 in chloroform
mp	~258 °C (dec.)
storage temp.	2-8°C

Description

Biochem/physiol Actions

Metabolite in the indole alkaloid biosynthesis (serpentine production); found naturally in various plants such as Rauwolfia spp., Catharanthus roseus, and Mitragyna speciosa^[5][1][3]. It shows antimicrobial activity^[4], and is used as an anti-hypertensive and sedative.

Application

Ajmalicine (δ-Yohimbine, Py-Tetrahydroserpentine, Raubasine) is an alkaloid used to study its effects as an antagonist of adrenergic and nicotinic receptors.

Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure.^[1] It has been marketed under numerous brand names including Card-Lamuran, Circolene, Cristanyl, Duxil, Duxor, Hydroxysarpon, Iskedyl, Isosarpan, Isquebral, Lamuran, Melanex, Raunatin, Saltucin Co, Salvalion, and Sarpan.

PRICE

$5494.56/KG OR $2497.52/IB

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