United States Pharmacopeia (USP) Reference Standard
Synonym: D-Mannitol, Mannite
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Empirical Formula (Hill Notation) C6H14O6
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Molecular Weight 182.17
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Beilstein Registry
Number 1721898
Properties
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Related Categories
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InChI Key
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FBPFZTCFMRRESA-KVTDHHQDSA-N
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form
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neat
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mp
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167-170 °C(lit.)
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format
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neat
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Mannitol is a type of sugar alcohol which is also used as a medication.As a sugar, it is often used as a sweetener in diabetic food, as it is
poorly absorbed from the intestines.[1] As a medication, it is used to decrease high pressures in the
eyes, seen in glaucoma, and to lower increased intracranial pressure.[3][2] Medically, it is given by injection. Effects typically begin
within 15 minutes and last up to 8 hours.
Detailed description
Common side effects from medical use include electrolyte problems and dehydration.[4] Other serious side
effects may include worsening heart failure and kidney problems.[4][2] It is unclear if use
is safe in pregnancy. Mannitol is in the osmotic diuretic family of
medications and works by pulling fluid from the brain and eyes.[4]
The discovery of mannitol is attributed to Joseph Louis Proust in 1806.[5] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[6] The wholesale cost
in the developing world is about US$1.12 to
5.80 a dose. In the United
States, a course of treatment costs $25 to 50. It was originally
made from the flowering ash and called manna after its supposed
resemblance to the Biblical food.
PRICE
$361186.10/KG OR $164175.5/IB
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