99%
Synonym: 2-Isopropyl-5-methylcyclohexanol,
Hexahydrothymol
·
Empirical Formula
(Hill Notation) C10H20O
·
Molecular
Weight 156.27
·
Beilstein
Registry Number 3194263
Properties
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Related Categories
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vapor pressure
|
0.8 mmHg ( 20 °C)
|
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InChI Key
|
NOOLISFMXDJSKH-UHFFFAOYSA-N
|
|
assay
|
99%
|
|
bp
|
216 °C(lit.)
|
|
mp
|
34-36 °C(lit.)
|
|
density
|
0.89 g/mL at 25 °C(lit.)
|
Menthol is an organic
compound made synthetically or obtained from corn mint, peppermint, or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room
temperature and melts slightly above. The main form of
menthol occurring in nature is (−)-menthol,
which is assigned the (1R,2S,5R) configuration. Menthol has local
anesthetic and counterirritant qualities, and it is widely used to relieve minor throat
irritation.
Menthol also acts as a weak kappa opioid receptor agonist.
Detailed description
Applications
Menthol is included in many products for a variety
of reasons. These include:
·
In nonprescription
products for short-term relief of minor sore throat and minor mouth or throat
irritation.
·
As an antipruritic to
reduce itching.
·
As a topical analgesic,
it is used to relieve minor aches and pains, such as muscle cramps, sprains,
headaches and similar conditions, alone or combined with chemicals such as camphor, eucalyptus oil or capsaicin. In Europe, it tends to
appear as a gel or a cream, while in the U.S., patches and body sleeves are
very frequently used.
·
In certain medications
used to treat sunburns, as it provides a
cooling sensation (then often associated with aloe).
·
As a smoking tobacco additive in some cigarette brands, for flavor, and
to reduce throat and sinus irritation caused by smoking. Menthol also increases
nicotine receptor density,[14] increasing the addictive
potential of tobacco products.[15][16]
·
Commonly used in oral hygiene products and bad-breath
remedies, such as mouthwash, toothpaste, mouth and
tongue-spray, and more generally as a food flavor agent; e.g., in chewing gum, candy.
·
In a soda to be mixed with water
it is used to obtain a very low alcohol drink or pure (brand Ricqlès which
contains 80% alcohol in France); the alcohol is also used to alleviate nausea, in particular motion sickness,
by pouring a few drops on a lump of sugar.
·
In perfumery, menthol is used to prepare
menthyl esters to emphasize floral notes (especially rose).
·
In first aid products
such as "mineral ice" to produce a cooling effect as a substitute for
real ice in the absence of water or electricity (pouch, body patch/sleeve or
cream).
·
In various patches
ranging from fever-reducing patches applied to children's foreheads to
"foot patches" to relieve numerous ailments (the latter being much
more frequent and elaborate in Asia, especially Japan: some varieties use "functional protrusions", or
small bumps to massage ones feet as well as soothing them and cooling them
down).
·
In some beauty products
such as hair conditioners, based on natural ingredients (e.g., St. Ives).
In organic chemistry, menthol is used as
a chiral auxiliary in asymmetric synthesis. For example, sulfinate esters made from sulfinyl
chlorides and menthol
can be used to make enantiomerically pure sulfoxides by
reaction with organolithium
reagents or Grignard reagents. Menthol reacts
with chiral carboxylic acids to give diastereomic menthyl esters, which are
useful for chiral resolution.
Packaging
5, 100, 500 g in poly bottle
PRICE
$5032.95/KG OR $2287.70/IB
For more information:
mobile: +2348039721941
contact person: emeaba uche
e-mail: emeabau@yahoo.com
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