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CAS Number 6106-04-3
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Linear Formula NaOOCCH2CH2CH(NH2)COOH ·
H2O
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Molecular Weight 187.13
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Beilstein Registry
Number 4164348
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MDL number MFCD00150138
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PubChem Substance ID 329750495
Monosodium glutamate (MSG, also known as sodium
glutamate) is the sodium salt of glutamic acid, one of the most abundant naturally
occurring non-essential amino acids.[Manuf. 1] Monosodium glutamate is found naturally in tomatoes, cheese and other foods.
Detailed description
MSG is used in the food industry as a flavor
enhancer with an umami taste that intensifies the meaty,
savory flavor of food, as naturally occurring glutamate does in foods such as
stews and meat soups.[2][3] It was first
prepared in 1908 by Japanese biochemist Kikunae Ikeda, who was trying to isolate and
duplicate the savory taste of kombu,
an edible seaweed used as a base for many Japanese soups. MSG as a flavor
enhancer balances, blends, and rounds the perception of other tastes.[4][5]
The U.S. Food and Drug
Administration has given MSG its generally recognized
as safe (GRAS) designation.[Gov. 2] A popular belief is
that large doses of MSG can cause headaches and other feelings
of discomfort, known as "Chinese restaurant
syndrome," but double-blind tests fail to find evidence
of such a reaction.[Gov. 2][6] The European Union classifies it as a food additive permitted in certain
foods and subject to quantitative limits. MSG has the HS code 29224220 and the E number E621.
Use
Pure MSG is reported not to have a pleasant taste
until it is combined with a savory aroma.[Manuf. 2] The basic sensory
function of MSG is attributed to its ability to enhance savory taste-active
compounds when added in the proper concentration.[4] The optimum
concentration varies by food; in clear soup, the pleasure score rapidly falls
with the addition of more than one gram of MSG per 100 mL.[7]
The sodium content (in mass percent) of MSG, 12%, is
about one-third of that in sodium chloride (39%), due to the greater mass of
the glutamate counterion.[Manuf. 3] Although other salts
of glutamate have been used in low-salt soups, they are less palatable than MSG.
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