Saturday, 7 October 2017

GLYOXAL BIS(SODIUM HYDROGEN SULFITE) ADDUCT HYDRATE[NaHSO3]


·         CAS Number 517-21-5

·         Linear Formula OHCCHO · 2NaHSO3

·         Molecular Weight 266.16 (anhydrous basis)
·          Beilstein Registry Number 3898061

·          EC Number 208-233-1

·          MDL number MFCD00149541
·          PubChem Substance ID 57651265


Sodium bisulfite (sodium hydrogen sulfite) is a chemical compound with the chemical formula NaHSO3. Sodium bisulfite is a food additive with E number E222. 
Detailed description
This salt of bisulfite can be prepared by bubbling sulfur dioxide in a solution of sodium carbonate in water. Sodium bisulfite in contact with chlorine bleach (aqueous solution of sodium hypochlorite) will generate heat and form sodium bisulfate and sodium chloride.

Uses in food and FDA ban

While the related compound, sodium metabisulfite, is used in almost all commercial wines to prevent oxidation and preserve flavor, sodium bisulfite is sold by some home winemaking suppliers for the same purpose. In fruit canning, sodium bisulfite is used to prevent browning (caused by oxidation) and to kill microbes.
In the case of wine making, sodium bisulfite releases sulfur dioxide gas when added to water or products containing water. The sulfur dioxide kills yeasts, fungi, and bacteria in the grape juice before fermentation. When the sulfur dioxide levels have subsided (about 24 hours), fresh yeast is added for fermentation.
It is later added to bottled wine to prevent the formation of vinegar if bacteria are present, and to protect the color, aroma and flavor of the wine from oxidation, which causes browning and other chemical changes. The sulfur dioxide quickly reacts with oxidation by-products and prevents them from causing further deterioration.
Sodium bisulfite is also added to leafy green vegetables in salad bars and elsewhere, to preserve apparent freshness, under names like LeafGreen. The concentration is sometimes high enough to cause severe allergic reactions.
On July 8, 1986, sodium bisulfite was banned from use by the FDA on fresh fruits and vegetables in the United States following the deaths of 13 people and many illnesses, mainly among asthmatics.

Bisulfite DNA sequencing

Sodium bisulfite is used in the analysis of methylation status of cytosines in DNA.
In this technique, sodium bisulfite deaminates cytosine into uracil, but does not affect 5-methylcytosine, a methylated form of cytosine with a methyl group attached to carbon 5.
When the bisulfite-treated DNA is amplified via polymerase chain reaction, the uracil is amplified as thymine and the methylated cytosines are amplified as cytosine. DNA sequencing techniques are then used to read the sequence of the bisulfite-treated DNA. Those cytosines that are read as cytosines after sequencing represent methylated cytosines, while those that are read as thymines represent unmethylated cytosines in the genomic DNA.

Industrial uses

Sodium bisulfite is a common reducing agent in the chemical industry, as it readily reacts with dissolved oxygen:
2 NaHSO3 + O2 → 2 NaHSO4
It is usually added to large piping systems to prevent oxidative corrosion. In biochemical engineering applications, it is helpful to maintain anaerobic conditions within a reactor. Sodium bisulfite should not be confused with sodium bisulfate which is used as a pH lowering chemical for swimming pools.
In drinking water treatment, sodium bisulfite is often added after super chlorination, to reduce the residual chlorine before discharging to the service reservoir.
In wastewater treatment, sodium bisulfite is often added following disinfection with chlorine prior to discharging the effluent to the receiving water. Residual chlorine can have a negative impact on aquatic life.
In Steam Boilers, sodium bisulfite has been a reliable oxygen scavenger in boiler feedwater for approximately 60 years. This compound is characterized as having fast reaction times, low use-cost, years of proven performance, availability. Sodium bisulfite when used in steam boilers has FDA and USDA approvals.
  
PRICE
$217.12/KG OR $98.69/IB

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